Exploring the effect of social media in Personal Learning Environments in the university settings: analysing experiences and detecting future challenges

The concept of PLEs as connected learning and the shaping of them as a socio-material framework in which people learn, overlaps with the intrinsic characteristics of social media. Consequently, it is important to analyse how academic literature has treated the direct relationship between the two realities in the university sector. Accordingly, the objective of this work is to determine how this relationship has been treated with regards to contexts, authorship and positions, types of social media, objectives pursued, methodologies and results. Regarding methodology, we used the PICOC strategy to design the research questions and the PRISMA protocol to document the systematic review of academic production in SCOPUS and Web of Science between 2012 and 2021. We ultimately obtained a sample of 35 works. The findings show that use of media to build PLEs that meet users’ needs should be explored in greater depth and analysed by using particular methodologies to reach conclusions that help to drive them. Academic and professional promotion stand out among the major challenges in the use of social media in PLEs, as does the possibility of bringing together non-formal, formal, and informal areas to create learning

Optimización en los procesos de reporte de información de actividad

Este PFC consiste en el diseño e implementación de una aplicación contenida en una Intranet empresarial. Ésta planifica, ordena y centraliza toda la información de los distintos proyectos en curso gestionados en una consultora informática (Hiberus). Para el desarrollo de la aplicación, se ha utilizado Sharepoint 2010 así como otras herramientas como Sharepoint Designer 2010 o Viual Studio 2010, las cuales han permitido realizar las modificaciones más avanzadas

Academic Progress, Coping Strategies and Psychological Distress among Teacher Education Students

Academic performance among university students is a fundamental factor in the analysis of quality of higher education. Despite the large volume of research on academic performance, there are no conclusive results regarding the influence of some variables on it. While some studies find differences attributable to gender, age, or psychological factors, such as coping strategies, others conclude that they are inexistent or insignificant. This article seeks to deepen about how these variables influence the academic performance of trainee primary-school teachers. Educational improvements in a society are only possible if teacher training guarantees a high qualification of its teachers. In this article we analyze academic progress in a sample of 136 students and the effect of gender, age and coping strategies and psychological symptoms. From the data analysis it can be concluded that all the analyzed variables cause differences in academic performance in teacher students. Therefore, it will be necessary to establish improvement plans for this degree that meet these conditions

EHP-101 alleviates angiotensin II-induced fibrosis and inflammation in mice

Some cannabinoids showed anti-inflammatory and antifibrotic activities. EHP-101 is an oral lipidic formulation of the novel non-psychotropic cannabidiol aminoquinone VCE-004.8, which showed antifibrotic activity in murine models of systemic sclerosis induced by bleomycin. We herein examined the effect of EHP-101 on cardiac and other organ fibrosis in a mouse model induced by Angiotensin II. VCE-004.8 inhibited TGFβ- and Ang II-induced myofibroblast differentiation in cardiac fibroblasts detected by α-SMA expression. VCE-004.8 also inhibited Ang II-induced ERK 1 + 2 phosphorylation, NFAT activation and mRNA expression of IL1β, IL6, Col1A2 and CCL2 in cardiac fibroblasts. Mice infused with Ang II resulted in collagen accumulation in left ventricle, aortic, dermal, renal and pulmonary tissues; oral administration of EHP-101, Ajulemic acid and Losartan improved these phenotypes. In myocardial tissue, Ang II induced infiltration of T cells and macrophages together with the accumulation of collagen and Tenascin C; those were all reduced by either EHP-101 or Losartan treatment. Cardiac tissue RNA-Seq analyses revealed a similar transcriptomic signature for both treatments for inflammatory and fibrotic pathways. However, the gene set enrichment analysis comparing data from EHP-101 vs Losartan showed specific hallmarks modified only by EHP-101. Specifically, EHP-101 inhibited the expression of genes such as CDK1, TOP2A and MKi67 that are regulated to the E2 factor family of transcription factors. This study suggests that the oral administration of EHP-101 prevents and inhibits cardiac inflammation and fibrosis. Furthermore, EHP-101 inhibits renal, pulmonary and dermal fibrosis. EHP-101 could offer new opportunities in the treatment of cardiac fibrosis and other fibrotic diseases

Multivariate Analysis and Modelling of multiple Brain endOphenotypes: Let's MAMBO!

Imaging genetic studies aim to test how genetic information influences brain structure and function by combining neuroimaging-based brain features and genetic data from the same individual. Most studies focus on individual correlation and association tests between genetic variants and a single measurement of the brain. Despite the great success of univariate approaches, given the capacity of neu- roimaging methods to provide a multiplicity of cerebral phenotypes, the development and application of multivariate methods become crucial. In this article, we review novel methods and strategies focused on the analysis of multiple phenotypes and genetic data. We also discuss relevant aspects of multi-trait modelling in the context of neuroimag- ing data

Fixation of bioactive compounds to the cuticle of Artemia

Artemia is extensively used in aquaculture to feed early stages of cultured marine species. A problem associated with this practice is that Artemia fails to supply some essential nutrients. As a possible solution, we have devised a procedure to make Artemia a vehicle for exogenous nutrients and other bioactive compounds. It consists of the construction of chimeric proteins composed of a chitin-binding domain, which binds to the cuticle of Artemia, and a carrier domain that conveys a functional property. As confirmatory examples, we describe the successful fixation to Artemia's metanauplii of two hybrid proteins: a β-galactosidase from the thermophilic bacterium Thermotoga maritima and the jellyfish green fluorescent protein (GFP), both linked to the CBM2 chitin-binding domain from the hyperthermophilic archaeon Pyrococcus furiosus. Positive results of experiments carried out ex vivo and in vivo show the validity of this approach. The methodology used could become a general procedure for the attachment of different kinds of bioactive compounds, such as enzymes, hormones, antibiotics, etc., to the cuticle of Artemia as well as other arthropods. Statement of relevance: Our results overcome shortcomings of Artemia as a feedstock.En prensa2,04

Character strengths in Spanish music students: An exploratory study

The factors in the choice of musical instruments and how it influences and modifies the personality of the musicians are a common theme in research. However, less attention has been given to the formative effect of music on the character of music students, whose long-term commitment to acquiring professional competences as performers, teachers, conductors or composers can be examined using the research on Positive Psychology, which is mainly concerned with furthering people's psychological wellbeing. This paper profiles the virtues and character strengths of a sample of eighty Spanish students completing bachelor's degrees in music during the academic year 2016-2017, using the VIA Inventory of Strengths -free version (VIA-IS) (Peterson & Seligman, 2004) to analyse the respondents' key strengths. The survey showed high scores in judgment and lower scores in self-regulation. The results were contrasted with samples of students in bachelor's degrees in the social sciences

Obstructive uropathy secondary to ureteral inguinoscrotal hernia.

post-print2,18 M

La influencia de las Artes como motor de bienestar: un estudio exploratorio

Las funciones del arte han sido objeto de estudio de numerosas investigaciones en las últimas décadas, aunque son pocos los estudios centrados en conocer la vinculación entre el arte y bienestar desde el punto de vista del sujeto participante. En este trabajo se muestran los resultados de un estudio descriptivo exploratorio correlacional que analiza la vinculación entre el arte y el bienestar mediante un cuestionario on-line ad hoc, aplicado a  462 personas de diferente edad, sexo, nivel de estudios y experiencia artística. Una amplia mayoría de ellas considera que el arte siempre puede mejorar su estado anímico siendo la música el arte preferido  para ello. Algunos consideran que el arte es más eficaz que otras técnicas como el deporte para crear bienestar aunque la mayoría prefiere combinarlo con otras disciplinas. Las personas con una formación o experiencia artística son más proclives a usar cualquier manifestación artística para crear el bienestar.</p